Chemical Synthesis
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Recent papers in Chemical Synthesis
We wish to report here our initial efforts toward the total synthesis of the potent antitumor agent dictyostatin, describing a short and efficient synthesis of the C11–C23 fragment. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim,... more
The stereocontrolled synthesis of β-galactosyl-5-aza-sphinganines was accomplished with high efficiency by a novel and convergent strategy. The truncated β-galactosphinganine 5 was easily acylated with different long chains. Moreover, the... more
Ion exchange reactions between the Dion-Jacobson-type, triple-layered perovskite RbCa2Nb3O10 and calcium, strontium, and barium cations were investigated. Exchange occurs in all systems, but only the strontium and barium systems form... more
A complete set of platinum(II) solketal substituted phthalocyanines has been synthesized and characterized. To evaluate their potential as Type II photosensitizers for photodynamic therapy, comparative studies of their photophysical and... more
The preparation of 2-triazolyl- and 2-triazolylmethylpyrrolidines from L-proline and L-trans-4-hydroxyproline is described, along with their evaluation as chiral ligands in ruthenium-catalyzed asymmetric transfer hydrogenation. Modular... more
Some 35 years ago, I had the good fortune to be accepted into Ray Wu’s lab as a graduate student. Ray was already well known for his pioneering studies in DNA sequencing, and his lab was quietly humming with the excitement of the new... more
Tripodal peptide analogues were designed on the basis of the phosphotyrosine binding pocket of the Src SH2 domain and assayed for their ability to bind to fluorescein-labeled phosphopeptides. Fluorescence polarization assays showed that a... more
Xanthophylls are oxygenated carotenoids abun-dant in the human food supply. Lutein, zeaxanthin, and cryptoxanthin are major xanthophyll carotenoids in human plasma. The consumption of these xanthophylls is directly associated with... more